Label-free optical biosensors in the pandemic era

Abstract The research in the field of optical biosensors is continuously expanding, thanks both to introduction brand new technologies and ingenious use established methods. A awareness on potential societal impact this has arisen as a consequence Covid-19 pandemic. availability generation analytical tools enabling more accurate understanding bio-molecular processes or development distributed diagnostic devices with improved performance now greater demand clearly envisioned, but not yet achieved. In review, we focus emerging innovation opportunities conveyed by label-free biosensors. We review most recent innovations biosensor technology consideration their competitive selected application areas. operational simplicity implicit detection can be exploited novel rapid compact for applications. adaptability any molecular recognition conformational process facilitates integration DNA nanostructures carrying functions. high sensitivity nanoscale objects stimulates ultrasensitive systems down digital single binding events enhanced nanoparticles direct enumeration bio-nanoparticles like viruses.